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KMID : 0357920110450050529
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Korean Journal of Pathology
2011 Volume.45 No. 5 p.529 ~ p.531
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Childhood Asymmetry Labium Majus Enlargement
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Gu Mi-Jin
Kim Sang-Yoon
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Abstract
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Childhood asymmetry labium majus enlargement (CALME) is a disctinctive clinicopathologic entity of pre- and early puberty first described in 2005. It is defined as an expansion of normal soft tissues of the vulva. Although CALME is not a rare lesion, it has been called lipoma, fibroma, hamartoma, and fibrous hyperplasia. CALME is not a true neoplasm and is a physiologic growth in response to hormone. It may tend to resolve spontaneously and recur after surgical resection. We report four cases of CALME with a review of the literature. To the best of the knowledge, this is the first Korean report.
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KEYWORD
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Child, Vulva, Hypertrophy, Enlargement, Puberty
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